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Subtype-Directed Differentiation of Human iPSCs into Atrial and Ventricular Cardiomyocytes

1 Jun 2020

Abstract excerpt

The generation of homogeneous populations of subtype-specific cardiomyocytes derived from human induced pluripotent stem cells (hiPSCs) is crucial in cardiovascular disease modeling as well as in drug discovery and cardiotoxicity screenings. This protocol describes a simple, robust, and efficient monolayer-based differentiation of hiPSCs into defined atrial and ventricular cardiomyocytes. For complete details on...

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PMID: 33111079
DOI: 10.1016/j.xpro.2020.100026

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