Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotype and Clinical Outcomes of Titin Cardiomyopathy.

Journal of the American College of Cardiology - 31 Oct 2017

Tayal Upasana, Newsome Simon, Buchan Rachel, Whiffin Nicola, Halliday Brian, Lota Amrit, Roberts Angharad, Baksi A John, Voges Inga, Midwinter Will, Wilk Alijca, Govind Risha, Walsh Roddy, Daubeney Piers, Jarman Julian W E, Baruah Resham, Frenneaux Michael, Barton Paul J, Pennell Dudley, Ware James S, Prasad Sanjay K, Cook Stuart A

Abstract excerpt

BACKGROUND: Improved understanding of dilated cardiomyopathy (DCM) due to titin truncation (TTNtv) may help guide patient stratification. OBJECTIVES: The purpose of this study was to establish relationships among TTNtv genotype, cardiac phenotype, and outcomes in DCM. METHODS: In this prospective, observational cohort study, DCM patients underwent clinical evaluation, late gadolinium enhancement cardiovascular...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Cardiomyopathy, Dilated

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cohort Studies

Share to Connectin

Share to Follow-Up Studies

Share to Single-Blind Method

Share to Treatment Outcome

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 29073955
DOI: 10.1016/j.jacc.2017.08.063
PMCID: PMC5666113

Genes

TTN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotype and Clinical Outcomes of Titin Cardiomyopathy.PMID 29073955Read ↗

Dilated cardiomyopathy caused by truncating titin variants: long-term outcomes, arrhythmias, response to treatment and sex differences.Semantic proximity Read ↗

Truncating titin mutations are associated with a mild and treatable form of dilated cardiomyopathy.Semantic proximity Read ↗

Titin : an analysis of genetic variation and cardiac phenotypeSemantic proximity Read ↗

Integrated genetic and phenotypic assessment of dilated cardiomyopathySemantic proximity Read ↗

Role of titin in cardiomyopathy: from DNA variants to patient stratification.Semantic proximity Read ↗

Prevalence and clinical importance of titin truncating variants in adults without known congestive heart failureSemantic proximity Read ↗

Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease.Semantic proximity Read ↗

Genotype-phenotype correlations in patients with pathogenic/likely pathogenic titin variants from the Swiss Arrhythmogenic Cardiomyopathy Registry.Semantic proximity Read ↗

Clinical Phenotypes and Prognosis of Dilated Cardiomyopathy Caused by Truncating Variants in the TTN Gene.Semantic proximity Read ↗

Genetic epidemiology of titin-truncating variants in the etiology of dilated cardiomyopathySemantic proximity Read ↗

Titin-Related Dilated Cardiomyopathy: The Sequence of Events and The Role of Circulating Biomarkers in The Clinical AssessmentSemantic proximity Read ↗

Titin-related Cardiomyopathy: Is it a Distinct Disease?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.