Article
The clinical and genetic features in a cohort of mainland Chinese patients with thyrotoxic periodic paralysis.
BMC neurology - 21 Mar 2015
Li Xiaobing, Yao Sheng, Xiang Yining, Zhang Xiaolei, Wu Xiangbing, Luo Laimin, Huang Haihua, Zhu Min, Wan Hui, Hong Daojun
Abstract excerpt
BACKGROUND: Thyrotoxic periodic paralysis (TPP) is a life-threatening channelopathy manifesting as recurrent episodes of hypokalemia and muscle weakness in the presence of hyperthyroidism. Recent findings indicate defects of inward rectifying K+ (Kir) channels are associated with some TPP patients. The associations are not only found in Caucasian population (mainly Brazilian), but also in Singaporean population....
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