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Article

Eimeria bovis infections induce G1 cell cycle arrest and a senescence-like phenotype in endothelial host cells.

Parasitology - 1 Mar 2021

Velásquez Zahady D, López-Osorio Sara, Waiger Daniel, Manosalva Carolina, Pervizaj-Oruqaj Learta, Herold Susanne, Hermosilla Carlos, Taubert Anja

Abstract excerpt

Apicomplexan parasites are well-known to modulate their host cells at diverse functional levels. As such, apicomplexan-induced alteration of host cellular cell cycle was described and appeared dependent on both, parasite species and host cell type. As a striking evidence of species-specific reactions, we here show that Eimeria bovis drives primary bovine umbilical vein endothelial cells (BUVECs) into a...

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Identifiers

PMID: 33100232
DOI: 10.1017/S0031182020002097
PMCID: PMC7890351

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