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PBMCs are additional sites of productive infection of bovine papillomavirus type 2

28 Apr 2011

Abstract excerpt

Bovine papillomavirus type 2 (BPV-2) is an oncogenic virus infecting both epithelial and mesenchymal cells. Its life cycle, similar to other papillomaviruses (PVs), appears to be linked to epithelial differentiation. Human and bovine PVs have been known to reside in a latent, episomal form in PBMCs; therefore, it is believed that blood cells, like all mesenchymal cells, function as non-permissive carriers. Here,...

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PMID: 21525209
DOI: 10.1099/vir.0.031740-0

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