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Article

Noninvasive prenatal paternity determination using microhaplotypes: a pilot study.

BMC medical genomics - 23 Oct 2020

Wang Jaqueline Yu Ting, Whittle Martin R, Puga Renato David, Yambartsev Anatoly, Fujita André, Nakaya Helder I

Abstract excerpt

BACKGROUND: The use of noninvasive techniques to determine paternity prenatally is increasing because it reduces the risks associated with invasive procedures. Current methods, based on SNPs, use the analysis of at least 148 markers, on average. METHODS: To reduce the number of regions, we used microhaplotypes, which are chromosomal segments smaller than 200 bp containing two or more SNPs. Our method employs...

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Identifiers

PMID: 33097049
DOI: 10.1186/s12920-020-00806-w
PMCID: PMC7584091

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Source receipt: pubmed, retrieved 7 Sept 2026.

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