Article
Non-invasive prenatal paternity testing from maternal blood.
International journal of legal medicine - 1 Jan 2009
Wagner Jasenka, Dzijan Snjezana, Marjanović Damir, Lauc Gordan
Abstract excerpt
Prenatal paternity analysis can be performed only after invasive sampling of chorionic villi or amnionic fluid. Aiming to enable noninvasive paternity testing, we attempted to amplify fetal alleles from maternal plasma. Cell-free DNA was isolated from plasma of 20 pregnant women and amplified with ampFLSTR Identifiler and ampFLSTR Yfiler kits. Unfortunately, autosomal fetal alleles were heavily suppressed by...
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