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Article

The influence of genetic variability in IL1B and MIR146A on the risk of pleural plaques and malignant mesothelioma.

Radiology and oncology - 21 Oct 2020

Piber Petra, Vavpetic Neza, Goricar Katja, Dolzan Vita, Kovac Viljem, Franko Alenka

Abstract excerpt

Background Asbestos exposure is associated with the development of pleural plaques as well as malignant mesothelioma (MM). Asbestos fibres activate macrophages, leading to the release of inflammatory mediators including interleukin 1 beta (IL-1β). The expression of IL-1β may be influenced by genetic variability of IL1B gene or regulatory microRNAs (miRNAs). This study investigated the effect of polymorphisms in...

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Identifiers

PMID: 33085641
DOI: 10.2478/raon-2020-0057
PMCID: PMC7585336

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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