Article
BRCA1 and BRCA2 mutations in Japanese patients with ovarian, fallopian tube, and primary peritoneal cancer.
Cancer - 1 Jan 2016
Sakamoto Ikuko, Hirotsu Yosuke, Nakagomi Hiroshi, Ouchi Hidetaka, Ikegami Atsushi, Teramoto Katsuhiro, Amemiya Kenji, Mochizuki Hitoshi, Omata Masao
Abstract excerpt
BACKGROUND: The contribution of BRCA1 and BRCA2 to ovarian cancer in Japanese patients is still unclear. This study investigated the frequency of germline mutations in BRCA1/2 in Japanese patients with ovarian, peritoneal, or fallopian tube cancer, regardless of their family histories, which were suggestive of hereditary breast and ovarian cancer. METHODS: Ninety-five unselected women with ovarian cancer who were...
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