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Ethnic and geographic diversity of chronic lymphocytic leukaemia.

Leukemia - 1 Feb 2021

Yang Shenmiao, Varghese Abraham M, Sood Nitin, Chiattone Carlos, Akinola Norah O, Huang Xiaojun, Gale Robert Peter

Abstract excerpt

East Asians, Asian Indians and Amerindians have a five to ten-fold lower age-adjusted incidence rate (AAIR) of chronic lymphocytic leukaemia (CLL) compared with persons of predominately European descent. The data we review suggest a genetic rather than environmental basis for this discordance. All these populations arose from a common African Black ancestor but different clades have different admixture with...

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PMID: 33077870
DOI: 10.1038/s41375-020-01057-5

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