Article
Development of a physiologically based pharmacokinetic (PBPK) population model for Chinese elderly subjects
17 Oct 2020
Abstract excerpt
Aims This study aims to develop and verify a physiologically based pharmacokinetic (PBPK) population model for the Chinese geriatric population in Simcyp. Methods Firstly, physiological information for the Chinese geriatric population was collected and later employed to develop the Chinese geriatric population model by recalibration of corresponding physiological parameters in the Chinese adult population model...
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