Article
A Role for HAPLN1 During Phenotypic Modulation of Human Lung Fibroblasts In Vitro.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society - 1 Nov 2020
Evanko Stephen P, Gooden Michel D, Kang Inkyung, Chan Christina K, Vernon Robert B, Wight Thomas N
Abstract excerpt
Hyaluronan and proteoglycan link protein 1 (HAPLN1) stabilizes interactions between two important extracellular matrix (ECM) macromolecules, versican and hyaluronan, which facilitate proliferation of fibroblasts and their conversion to myofibroblasts. However, the role of HAPLN1 in these events has not been studied. Using immunocytochemistry, cellular and ECM locations of HAPLN1 were evaluated in cultured human...
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