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A miR-182 variant and risk of hepatocellular carcinoma in a southern Chinese population.

Human genomics - 15 Oct 2020

Qiu Moqin, Liu Yingchun, Lin Qiuling, Zhou Zihan, Jiang Yanji, Huo Rongrui, Liang Xiumei, Yu Xiangyuan, Cao Ji, Zhou Xianguo, Yu Hongping

Abstract excerpt

MicroRNAs (miRNAs) play important roles in the regulation of gene expression at the posttranscriptional level and are involved in human carcinogenesis. The aim of the current study was to investigate the associations between miR-182 single nucleotide polymorphisms and HCC risk in a southern Chinese population. In this case-control study of 863 HCC patients and 908 cancer-free controls, we performed genotyping of...

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PMID: 33059751
DOI: 10.1186/s40246-020-00289-x
PMCID: PMC7559205

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