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Article

Genotype-phenotype correlation of HbH disease in northern Iraq.

BMC medical genetics - 15 Oct 2020

Shamoon Rawand P, Yassin Ahmed K, Polus Ranan K, Ali Mohamad D

Abstract excerpt

BACKGROUND: HbH disease results from dysfunction of three, less commonly two, α-globin genes through various combinations of deletion and non-deletion mutations. Characterization of the mutations and the underlying genotypes is fundamental for proper screening and prevention of thalassaemia in any region. The aim of this study was to explore the genetic arrangements of HbH disease and to correlate the genotypes...

Topics

Adolescent
Adult
Aged
Child
Child, Preschool
Female
Genetic Association Studies
Genotype
Hemoglobin H
Humans
Infant
Iraq
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Mutation

Phenotype

Young Adult

alpha-Globins

Source

Open in PubMed Open full text

Identifiers

PMID: 33059634
DOI: 10.1186/s12881-020-01141-8
PMCID: PMC7559146

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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