Article
Prevention of acute rejection after rescue with Belatacept by association of low-dose Tacrolimus maintenance in medically complex kidney transplant recipients with early or late graft dysfunction.
PloS one - 1 Jan 2020
Gallo Ester, Abbasciano Isabella, Mingozzi Silvia, Lavacca Antonio, Presta Roberto, Bruno Stefania, Deambrosis Ilaria, Barreca Antonella, Romagnoli Renato, Mella Alberto, Fop Fabrizio, Biancone Luigi
Abstract excerpt
BACKGROUND: Increased acute rejection risk in rescue protocols with Belatacept may limit its use particularly in medically complex patients where preexisting increased risk of rejection couples with CNI toxicity. METHODS: Retrospective analysis was performed in 19 KTs shifted to a Belatacept-based immunosuppression with low-dose Tacrolimus (2-3 ng/mL) after evidence of allograft disfunction, including patients...
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