Article
Fermentative production of Vitamin E tocotrienols in Saccharomyces cerevisiae under cold-shock-triggered temperature control.
Nature communications - 14 Oct 2020
Shen Bin, Zhou Pingping, Jiao Xue, Yao Zhen, Ye Lidan, Yu Hongwei
Abstract excerpt
The diverse physiological functions of tocotrienols have listed them as valuable supplementations to α-tocopherol-dominated Vitamin E products. To make tocotrienols more readily available, tocotrienols-producing S. cerevisiae has been constructed by combining the heterologous genes from photosynthetic organisms with the endogenous shikimate pathway and mevalonate pathway. After identification and elimination of...
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