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Safe and efficient peripheral blood stem cell collection in patients with sickle cell disease using plerixafor

13 Feb 2020

Abstract excerpt

Hematopoietic stem cell (HSC) gene therapy is potentially curative for sickle cell disease (SCD); 1 however, options for HSC collection are limited in this population, 2-4 and investigation of the collection, efficiency, and safety of peripheral blood (PB) mobilization with plerixafor from start to finish is needed. Here we describe consistent, safe, and sufficient PB HSC collection and processing after...

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Identifiers

PMID: 33054091
DOI: 10.3324/haematol.2019.236182

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