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GMP-compatible manufacturing of three iPS cell lines from human peripheral blood

11 Feb 2019

Abstract excerpt

The utilization of human induced pluripotent stem cells (hiPSCs) for disease modeling and drug discovery is already reality, and several first-in-man-applications as cellular therapeutics have been initiated. Implementation of good manufacturing practice (GMP)-compliant protocols for the generation of hiPSC lines is crucial to increase the application safety as well as to fulfil the legal requirements for...

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PMID: 30772682
DOI: 10.1016/j.scr.2019.101394

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