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Stem cell transplantation in sickle cell disease: therapeutic potential and challenges faced

8 Jun 2018

Abstract excerpt

INTRODUCTION: Sickle cell disease (SCD) is the most common inherited hemoglobinopathy worldwide, and is a life-limiting disease with limited therapeutic options to reduce disease severity. Despite being a monogenic disorder, the clinical phenotypes of SCD are variable, with few reliable predictors of disease severity easily identifying patients where the benefits of curative therapy outweigh the risks. Allogeneic...

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PMID: 29883237
DOI: 10.1080/17474086.2018.1486703

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