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Article

Systems biology approach suggests new miRNAs as phenotypic stability factors in the epithelial-mesenchymal transition.

Journal of the Royal Society, Interface - 1 Oct 2020

Silveira Daner A, Gupta Shantanu, Mombach José Carlos M

Abstract excerpt

The epithelial-mesenchymal transition (EMT) is a cellular programme on which epithelial cells undergo a phenotypic transition to mesenchymal ones acquiring metastatic properties such as mobility and invasion. TGF-β signalling can promote the EMT process. However, the dynamics of the concentration response of TGF-β-induced EMT is not well explained. In this work, we propose a logical model of TGF-β dose dependence...

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Identifiers

PMID: 33050781
DOI: 10.1098/rsif.2020.0693
PMCID: PMC7653381

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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