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Article

Dynamics of the feedback loops required for the phenotypic stabilization in the epithelial‐mesenchymal transition

17 Sept 2019

Abstract excerpt

The epithelial-mesenchymal transition (EMT) is a complex mechanism in which cells undergo a transition from epithelial to mesenchymal phenotypes (there is also an intermediary hybrid state) in response to microenvironmental alterations and aberrant stimuli triggered by molecules such as TGF-β. Recent studies in breast cancer progression reported new feedback loops and new participant molecules such as microRNAs...

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PMID: 31529614
DOI: 10.1111/febs.15062

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