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Article

MicroRNA and MicroRNA-Target Variants Associated with Autism Spectrum Disorder and Related Disorders.

Genes - 26 Jul 2022

Wong Anthony, Zhou Anbo, Cao Xiaolong, Mahaganapathy Vaidhyanathan, Azaro Marco, Gwin Christine, Wilson Sherri, Buyske Steven, Bartlett Christopher W, Flax Judy F, Brzustowicz Linda M, Xing Jinchuan

Abstract excerpt

Autism spectrum disorder (ASD) is a childhood neurodevelopmental disorder with a complex and heterogeneous genetic etiology. MicroRNA (miRNA), a class of small non-coding RNAs, could regulate ASD risk genes post-transcriptionally and affect broad molecular pathways related to ASD and associated disorders. Using whole-genome sequencing, we analyzed 272 samples in 73 families in the New Jersey Language and Autism...

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Identifiers

PMID: 35893067
DOI: 10.3390/genes13081329
PMCID: PMC9329941

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