Article
TssA-TssM-TagA interaction modulates type VI secretion system sheath-tube assembly in Vibrio cholerae.
Nature communications - 8 Oct 2020
Stietz Maria Silvina, Liang Xiaoye, Li Hao, Zhang Xinran, Dong Tao G
Abstract excerpt
The type VI protein secretion system (T6SS) is a powerful needle-like machinery found in Gram-negative bacteria that can penetrate the cytosol of receiving cells in milliseconds by physical force. Anchored by its membrane-spanning complex (MC) and a baseplate (BP), the T6SS sheath-tube is assembled in a stepwise process primed by TssA and terminated by TagA. However, the molecular details of its assembly remain...
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