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Article

Type VI secretion system sheath inter-subunit interactions modulate its contraction.

EMBO reports - 1 Feb 2018

Brackmann Maximilian, Wang Jing, Basler Marek

Abstract excerpt

Secretion systems are essential for bacteria to survive and manipulate their environment. The bacterial type VI secretion system (T6SS) generates the force needed for protein translocation by the contraction of a long polymer called sheath. The sheath is a six-start helical assembly of interconnected VipA/VipB subunits. The mechanism of T6SS sheath contraction is unknown. Here, we show that elongating the...

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Identifiers

PMID: 29222345
DOI: 10.15252/embr.201744416
PMCID: PMC5797969

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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