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Article

[Something new in the genetics of monogenic obesity and its insights into pathophysiology].

Medecine sciences : M/S - 1 Oct 2020

Baron Morgane, Froguel Philippe, Bonnefond Amélie

Abstract excerpt

Obesity is a complex, multifactorial disorder. About 5% of obese patients actually present with a monogenic form of obesity where only one mutation is sufficient to cause the disease. So far, the genes that have been found to be mutated in these monogenic forms play a key role in the leptin/melanocortin pathway which is mainly active in the hypothalamus and which regulates food intake and energy expenditure. Our...

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Source

Identifiers

PMID: 33026327
DOI: 10.1051/medsci/2020156

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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