[Monogenic human obesity: role of the leptin-melanocortin system in the regulation of food intake and body weight in humans].

doi:10.4321/s1137-66272012000200010

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Article

[Monogenic human obesity: role of the leptin-melanocortin system in the regulation of food intake and body weight in humans].

Anales del sistema sanitario de Navarra - 1 Jan 2000

González-Jiménez E, Aguilar Cordero M J, Padilla López C A, García García I

Abstract excerpt

Human obesity is a disorder of multifactorial origin in which genetic and environmental factors are involved. To understand the mechanisms regulating energy intake and fat accumulation in the body, it is important to study the genetic alterations causing monogenic obesity. Most of the genes involved in monogenic obesity are associated with the leptin-melanocortin system; hence the importance of studying this...

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PMID: 22948429
DOI: 10.4321/s1137-66272012000200010

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