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Article

Distinct clonal evolution in a case with anaplastic embryonal rhabdomyosarcoma.

Pediatrics international : official journal of the Japan Pediatric Society - 1 Jul 2021

Kato Keisuke, Yoshimi Ai, Noda Asami, Otani Haruo, Hojo Hiroshi, Tanaka Mio, Tanaka Yukichi, Ito Yumi, Nishimura Riki, Takita Junko, Yanai Toshihiro, Koike Kazutoshi, Tsuchida Masahiro

Abstract excerpt

BACKGROUND: Clonal evolution of malignancy is a complex process related to intratumoral heterogeneity, as recent studies have also demonstrated in rhabdomyosarcoma. The purpose of this study is to present a distinct clonal feature of a case with anaplastic embryonal type rhabdomyosarcoma (ERMS) using molecular analysis. METHODS: A five-year-old girl developed a metastatic pelvic tumor. We cultured neoplastic...

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Identifiers

PMID: 33021000
DOI: 10.1111/ped.14499

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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