Article
Clonality analysis of pediatric multiple tumors: two case reports and laboratory investigation.
Journal of pediatric hematology/oncology - 1 Apr 2006
Giunti Laura, Bernini Gabriella, Forni Marco, Tucci Fabio, Wheeler Elisabeth, Sardi Iacopo
Abstract excerpt
We examined the possibility of using microsatellite and mitochondrial DNA polymorphisms as markers to detect the clonal origin of tumor cells found in the same patient. We considered two children with complex tumor diseases: one with supratentorial primitive neuroectodermal tumors (PNET) and a hepatic rhabdoid tumor and another with brain and abdominal rhabdoid tumors. In the first patient we found an mtDNA...
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