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Idylla microsatellite instability assay versus mismatch repair immunohistochemistry: a retrospective comparison in gastric adenocarcinoma

5 Oct 2020

Abstract excerpt

Up to 22% of all gastric adenocarcinomas are of the microsatellite instability (MSI) subtype. This subtype may not benefit from conventional adjuvant chemotherapy but does respond to novel immunotherapies. A proportion of MSI gastric adenocarcinomas are associated with inherited disease, inferring an opportunity to screen for further cancers in the patient while also identifying at-risk relatives. Although the...

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PMID: 33020177
DOI: 10.1136/jclinpath-2020-207033

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