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Article

Genetic variants in Hippo signalling pathway-related genes affect the risk of colorectal cancer.

Archives of toxicology - 1 Jan 2021

Shen Hengyang, Meng Yixuan, Hu Tao, Li Shuwei, Du Mulong, Xin Junyi, Gu Dongying, Wang Meilin, Fu Zan

Abstract excerpt

The Hippo signalling pathway plays a crucial role in carcinogenesis. Therefore, we hypothesized that genetic variants in genes related to this pathway are associated with the colorectal cancer risk. A case-control study including 1150 patients and 1342 controls was performed to assess the association of genetic variants of genes involved in the Hippo signalling pathway with the risk of colorectal cancer. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33011827
DOI: 10.1007/s00204-020-02910-3

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