Article
Genome-Wide Association Analysis of Neonatal White Matter Microstructure.
Cerebral cortex (New York, N.Y. : 1991) - 5 Jan 2021
Zhang J, Xia K, Ahn M, Jha S C, Blanchett R, Crowley J J, Szatkiewicz J P, Zou F, Zhu H, Styner M, Gilmore J H, Knickmeyer R C
Abstract excerpt
A better understanding of genetic influences on early white matter development could significantly advance our understanding of neurological and psychiatric conditions characterized by altered integrity of axonal pathways. We conducted a genome-wide association study (GWAS) of diffusion tensor imaging (DTI) phenotypes in 471 neonates. We used a hierarchical functional principal regression model (HFPRM) to perform...
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