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Identification of a pocket factor that is critical to Zika virus assembly

2 Oct 2020

Abstract excerpt

Zika virus (ZIKV) is an emerging mosquito borne flavivirus and a major public health concern causing severe disease. Due to the presence of a lipid membrane and structural heterogeneity, attaining an atomic resolution structure is challenging, but important to understand virus assembly and life cycle mechanisms that offer distinct targets for therapeutic intervention. We here use subvolume refinement to achieve a...

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PMID: 33009400
DOI: 10.1038/s41467-020-18747-4

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