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Article

CD-loop Extension in Zika Virus Envelope Protein Key for Stability and Pathogenesis.

The Journal of infectious diseases - 5 Dec 2017

Gallichotte Emily N, Dinnon Kenneth H, Lim Xin-Ni, Ng Thiam-Seng, Lim Elisa X Y, Menachery Vineet D, Lok Shee-Mei, Baric Ralph S

Abstract excerpt

With severe disease manifestations including microcephaly, congenital malformation, and Guillain-Barré syndrome, Zika virus (ZIKV) remains a persistent global public health threat. Despite antigenic similarities with dengue viruses, structural studies have suggested the extended CD-loop and hydrogen-bonding interaction network within the ZIKV envelope protein contribute to stability differences between the viral...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28968838
DOI: 10.1093/infdis/jix473
PMCID: PMC5853241

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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