Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

2A and 2A-like Sequences: Distribution in Different Virus Species and Applications in Biotechnology

26 Oct 2021

Abstract excerpt

2A is an oligopeptide sequence that mediates a ribosome "skipping" effect and can mediate a co-translation cleavage of polyproteins. These sequences are widely distributed from insect to mammalian viruses and could act by accelerating adaptive capacity. These sequences have been used in many heterologous co-expression systems because they are versatile tools for cleaving proteins of biotechnological interest. In...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CRISPR and Genetic Engineering
Share to Viral Infections and Immunology Research
Share to Viral Infectious Diseases and Gene Expression in Insects

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34834965
DOI: 10.3390/v13112160

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 18 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

2A and 2A-like Sequences: Distribution in Different Virus Species and Applications in BiotechnologyPMID 34834965Read ↗

Picornavirus Evolution: Genomes Encoding Multiple 2A<sup>NPGP</sup> Sequences – Biomedical and Biotechnological UtilitySemantic proximity Read ↗

New Short RNA Motifs Potentially Relevant in the Severe Acute Respiratory Syndrome Coronavirus 2 GenomeSemantic proximity Read ↗

Structural diversity and phylogenetic distribution of valyl tRNA-like structures in viruses.Semantic proximity Read ↗

Modifications to the Foot-and-Mouth Disease Virus 2A Peptide: Influence on Polyprotein Processing and Virus Replication.Semantic proximity Read ↗

The 2A proteins of three diverse picornaviruses are related to each other and to the H-rev107 family of proteins involved in the control of cell proliferationSemantic proximity Read ↗

SARS-CoV-2 uses a multipronged strategy to impede host protein synthesisSemantic proximity Read ↗

2Apro is a multifunctional protein that regulates the stability, translation and replication of poliovirus RNASemantic proximity Read ↗

Inhibition of SARS-CoV-2 by Targeting Conserved Viral RNA Structures and SequencesSemantic proximity Read ↗

Extreme GC3 Codon Bias in a Novel Brown Seaweed Virus Results in Pseudoambigrammatic CharacteristicsSemantic proximity Read ↗

The ‘cleavage’ activities of foot-and-mouth disease virus 2A site-directed mutants and naturally occurring ‘2A-like’ sequencesSemantic proximity Read ↗

Comparative sequence analysis.Semantic proximity Read ↗

Cross- and Co-Packaging of Retroviral RNAs and Their ConsequencesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.