Article
Defining the First Part of the Oncogenic KRAS Journey.
Cell stem cell - 1 Oct 2020
Osborne Jihan K, Minna John D
Abstract excerpt
Discovered as a proto-oncogene 40 years ago, mutations in KRAS exist in ∼30% of all human cancers. In this issue of Cell Stem Cell,Dost et al. (2020) combine the power of analyzing organoid cultures, patient samples, and mouse models with scRNA-seq to elucidate early events occurring with oncogenic KRAS activation.
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