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Article

A genotype imputation method for de-identified haplotype reference information by using recurrent neural network.

PLoS computational biology - 1 Oct 2020

Kojima Kaname, Tadaka Shu, Katsuoka Fumiki, Tamiya Gen, Yamamoto Masayuki, Kinoshita Kengo

Abstract excerpt

Genotype imputation estimates the genotypes of unobserved variants using the genotype data of other observed variants based on a collection of haplotypes for thousands of individuals, which is known as a haplotype reference panel. In general, more accurate imputation results were obtained using a larger size of haplotype reference panel. Most of the existing genotype imputation methods explicitly require the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 33001993
DOI: 10.1371/journal.pcbi.1008207
PMCID: PMC7529210

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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