Article

Rapid, Reference-Free Human Genotype Imputation with Denoising Autoencoders

2021-12-02

Abstract excerpt

Genotype imputation is a foundational tool for population genetics. Standard statistical imputation approaches rely on the co-location of large whole-genome sequencing-based reference panels, powerful computing environments, and potentially sensitive genetic study data. This results in computational resource and privacy-risk barriers to access to cutting-edge imputation techniques. Moreover, the accuracy of curren...

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Literature Corpus work: bf7d26d1-65bc-5b0a-a5f0-b3d43330cb24
DOI: 10.1101/2021.12.01.470739

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