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Article

Late-onset Hereditary ATTR Amyloidosis with a Novel p.P63S (P43S) Transthyretin Variant.

Internal medicine (Tokyo, Japan) - 15 Feb 2021

Aono Yuya, Hamatani Yasuhiro, Katoh Nagaaki, Nakagawa Mayuko, Nakamura Katsuya, Yazaki Masahide, Kametani Fuyuki, Iguchi Moritake, Murakami Ikuko, Ogawa Hisashi, Abe Mitsuru, Akao Masaharu, Sekijima Yoshiki

Abstract excerpt

The patient was an 82-year-old Japanese man with no family history suggestive of amyloidosis. He developed bilateral leg edema and shortness of breath and was referred to our hospital. An electrocardiogram showed atrial fibrillation with right bundle branch block. Echocardiography showed concentric LV hypertrophy. An endomyocardial biopsy showed severe ATTR amyloid deposits. A genetic analysis of the...

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Identifiers

PMID: 32999234
DOI: 10.2169/internalmedicine.5615-20
PMCID: PMC7946494

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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