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Article

Transthyretin cardiac amyloidoses in older North Americans.

Journal of the American Geriatrics Society - 1 Apr 2012

Dharmarajan Kumar, Maurer Mathew S

Abstract excerpt

The amyloidoses are a group of hereditary or acquired disorders caused by the extracellular deposition of insoluble protein fibrils that impair tissue structure and function. All amyloidoses result from protein misfolding, a common mechanism for disorders in older persons, including Alzheimer's disease and Parkinson's disease. Abnormalities in the protein transthyretin (TTR), a serum transporter of thyroxine and...

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Identifiers

PMID: 22329529
DOI: 10.1111/j.1532-5415.2011.03868.x
PMCID: PMC3325376

Genes

TTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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