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Article

Cardiomyopathy in Swedish patients with the Gly53Glu and His88Arg transthyretin variants.

Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis - 1 Sept 2005

Holmgren Gösta, Hellman Urban, Anan Intissar, Lundgren Hans-Eric, Jonasson Jenni, Stafberg Christina, Fahoum Sämi, Suhr Ole B

Abstract excerpt

We report two new amyloidogenic transthyretin (TTR) variants detected in the Swedish population. One variant was previously unknown, while the other has been described in a French family. In Swedish patients, both variants have caused late-onset cardiac amyloidosis characterised by heart failure. In both cases, the diagnosis was determined by the detection of amyloid deposits in skin and/or rectal biopsies and...

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PMID: 16194874
DOI: 10.1080/13506120500223126

Genes

TTR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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