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Article

The major genetic risk factor for severe COVID-19 is inherited from Neanderthals.

Nature - 1 Nov 2020

Zeberg Hugo, Pääbo Svante

Abstract excerpt

A recent genetic association study1 identified a gene cluster on chromosome 3 as a risk locus for respiratory failure after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A separate study (COVID-19 Host Genetics Initiative)2 comprising 3,199 hospitalized patients with coronavirus disease 2019 (COVID-19) and control individuals showed that this cluster is the major genetic risk factor...

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Identifiers

PMID: 32998156
DOI: 10.1038/s41586-020-2818-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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