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Article

Predictive Value of FMO3 Variants on Plasma Disposition and Adverse Reactions of Oral Voriconazole in Febrile Neutropenia.

Pharmacology - 1 Jan 2021

Wang Xiaokang, Zhao Jingjing, Wen Ting, Liao Xueyi, Luo Bin

Abstract excerpt

BACKGROUND AND OBJECTIVES: With the increasing number of patients with febrile neutropenia (FN), voriconazole (VRC) has been widely used in hospitals for first-line treatment of FN. The study was designed for evaluating the influence of FMO3 mutation on the plasma disposition and adverse reactions of VRC in FN. MATERIALS AND METHODS: A single-center observational study was conducted in the inpatient ward for 4...

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PMID: 32998136
DOI: 10.1159/000510327

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