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Clinicopathological Features and Outcomes in Individuals with Breast Cancer and ATM, CHEK2, or PALB2 Mutations.

Annals of surgical oncology - 1 Jun 2021

Bergstrom Colin, Pence Colton, Berg Jordan, Partain Natalia, Sadeghi Navid, Mauer Caitlin, Pirzadeh-Miller Sara, Gao Ang, Li Hsiao, Unni Nisha, Syed Samira

Abstract excerpt

INTRODUCTION: The moderate-penetrance germline mutations ATM, CHEK2, and PALB2 are implicated in an increased risk of the development of breast cancer. Whether these mutations provide clinical utility to guide treatment strategies and prognosis remains unknown. METHODS: A retrospective case-control study from a tertiary institution compared patients with stage 0-III breast cancer, and positive for ATM, CHEK2, or...

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PMID: 32996020
DOI: 10.1245/s10434-020-09158-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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