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Article

Association of Moderate-Risk Breast Cancer Genes with Contralateral Prophylactic Mastectomy and Bilateral Disease.

Annals of surgical oncology - 1 Nov 2023

Zhang Jennifer Q, Dos Anjos Carlos Henrique, Sevilimedu Varadan, Crown Angelena, Amoroso Kimberly A, Pilewskie Melissa L, Robson Mark E, Gemignani Mary L

Abstract excerpt

BACKGROUND: The impact of ATM, CHEK2, and PALB2, the three most prevalent moderate-risk breast cancer genes, on surgical decision making is not well known. METHODS: Our retrospective study included patients with resectable non-metastatic breast cancer who underwent multigene panel testing between July 2014 and January 2020 with at least one genetic alteration (pathogenic or variant of uncertain significance [VUS]...

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Identifiers

PMID: 37661222
DOI: 10.1245/s10434-023-14141-8
PMCID: PMC11005956

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of Moderate-Risk Breast Cancer Genes with Contralateral Prophylactic Mastectomy and Bilateral Disease.PMID 37661222Read ↗

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Diagnosis, Management, and Surveillance for Patients With PALB2, CHEK2, and ATM Gene Mutations.Semantic proximity Read ↗

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