Article
Vascular Smooth Muscle Cell Derived from IPS Cell of Moyamoya Disease - Comparative Characterization with Endothelial Cell Transcriptome.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association - 1 Dec 2020
Tokairin Kikutaro, Hamauchi Shuji, Ito Masaki, Kazumata Ken, Sugiyama Taku, Nakayama Naoki, Kawabori Masahito, Osanai Toshiya, Houkin Kiyohiro
Abstract excerpt
BACKGROUND: Moyamoya disease (MMD) is an occlusive cerebrovascular disease, causing stroke in children and young adults with unknown etiology. The fundamental pathology is fibrocellular intimal thickening of cerebral arteries, in which vascular smooth muscle cells (VSMCs) are observed as one of the major cell types. Although the characteristics of circulating smooth muscle progenitor cells have been previously...
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