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Article

Machine learning based personalized drug response prediction for lung cancer patients.

Scientific reports - 7 Nov 2022

Qureshi Rizwan, Basit Syed Abdullah, Shamsi Jawwad A, Fan Xinqi, Nawaz Mehmood, Yan Hong, Alam Tanvir

Abstract excerpt

Lung cancers with a mutated epidermal growth factor receptor (EGFR) are a major contributor to cancer fatalities globally. Targeted tyrosine kinase inhibitors (TKIs) have been developed against EGFR and show encouraging results for survival rate and quality of life. However, drug resistance may affect treatment plans and treatment efficacy may be lost after about a year. Predicting the response to EGFR-TKIs for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36344580
DOI: 10.1038/s41598-022-23649-0
PMCID: PMC9640729

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