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Drug-microbiota interactions: an emerging priority for precision medicine

9 Oct 2023

Abstract excerpt

Individual variability in drug response (IVDR) can be a major cause of adverse drug reactions (ADRs) and prolonged therapy, resulting in a substantial health and economic burden. Despite extensive research in pharmacogenomics regarding the impact of individual genetic background on pharmacokinetics (PK) and pharmacodynamics (PD), genetic diversity explains only a limited proportion of IVDR. The role of gut...

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PMID: 37806986
DOI: 10.1038/s41392-023-01619-w

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