Article
Correlation between single nucleotide polymorphisms in CXCR4 microRNA binding site and the susceptibility to knee osteoarthritis in Han Chinese population.
Journal of clinical laboratory analysis - 1 Feb 2021
Wang Yang, Li Yanlin, Jia Di, Zheng Jiali, Wang Guoliang
Abstract excerpt
BACKGROUND: This study aimed to investigate the relationship between single nucleotide polymorphisms (SNPs) at the microRNA target sequence in CXCR4 and the susceptibility to knee osteoarthritis (KOA). METHODS: A total of 305 patients with KOA and 305 healthy controls were recruited into this study. The genotypes of CXCR4 rs1804029 and rs17848060 loci were analyzed. RESULTS: The susceptibility to KOA of CXCR4...
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