Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Utility of a multigene testing for preoperative evaluation of indeterminate thyroid nodules: A prospective blinded single center study in China.

Cancer medicine - 1 Nov 2020

Song Yuntao, Xu Guohui, Ma Tonghui, Zhu Yanli, Yu Hao, Yu Wenbin, Wei Wei, Wang Tianxiao, Zhang Bin

Abstract excerpt

BACKGROUND: Thyroid nodules are highly prevalent, with fine-needle aspiration (FNA) commonly used as the standard preoperative tool for their diagnosis. However, the method classifies some of the samples as indeterminate, leading to unnecessary surgery. In this study, we evaluated the value of next-generation sequencing (NGS) for cancer diagnosis in indeterminate thyroid nodules. MATERIALS AND METHODS: We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Beijing
Share to Biopsy, Fine-Needle

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Fusion

Share to Polycomb Repressive Complex 2

Share to Single-Blind Method

Share to Thyroid Neoplasms

Share to Thyroid Nodule

Share to Thyroidectomy

Source

Open in PubMed Open full text

Identifiers

PMID: 32976686
DOI: 10.1002/cam4.3450
PMCID: PMC7666727

Genes

SPOP
ZNF148
BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Utility of a multigene testing for preoperative evaluation of indeterminate thyroid nodules: A prospective blinded single center study in China.PMID 32976686Read ↗

Clinical value of multi-gene testing in distinguishing benign and malignant thyroid nodulesSemantic proximity Read ↗

Clinical value of multi-gene testing in distinguishing benign and malignant thyroid nodules.Semantic proximity Read ↗

Real-life utility of five-gene panel test in preoperative thyroid fine-needle aspiration biopsy: a large cohort of 740 patients study.Semantic proximity Read ↗

Risk stratification of indeterminate thyroid nodules by novel multigene testing: a study of Asians with a high risk of malignancy.Semantic proximity Read ↗

A Combination of BRAF and EZH1/SPOP/ZNF148 Three-Gene Mutational Classifier Improves Benign Call Rate in Indeterminate Thyroid Nodules.Semantic proximity Read ↗

Utilities of next-generation sequencing in the surgical management of thyroid nodules in China.Semantic proximity Read ↗

Molecular diagnosis for indeterminate thyroid nodules on fine needle aspiration: advances and limitations.Semantic proximity Read ↗

Diagnostic Utility of a Cost-Effective Four-Gene Next Generation Sequencing Panel for Predicting Papillary Thyroid Carcinoma in Indeterminate Thyroid Cytology: A Multicenter Study in China.Semantic proximity Read ↗

A five-gene panel refines differential diagnosis of thyroid nodules.Semantic proximity Read ↗

Diagnostic performance of next-generation sequencing and genetic profiling in thyroid nodules from a single center in ChinaSemantic proximity Read ↗

The actual and future role of molecular tests in thyroid pathology.Semantic proximity Read ↗

How genetics changed or will change the therapy in thyroid nodules with indeterminate cytology?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.