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Article

A five-gene panel refines differential diagnosis of thyroid nodules.

Journal of clinical laboratory analysis - 1 Sept 2021

Lu Sang-Yu, Chen Ying-Chao, Zhu Chen-Fang, Chen Jing, Zhou Qin-Yi, Zhang Man-Man, Zhang Qian-Yue, Lu Meng, Yang Liu, Wu Jing, Zhao Shuang-Xia, Song Huai-Dong, Ye Xiao-Ping

Abstract excerpt

BACKGROUND: Molecular testing for oncogenic mutations in fine-needle aspiration has showed high predictive value in identifying malignant lesions from thyroid nodules with indeterminate cytology. METHODS: To figure out an efficient and economical gene panel for most medical institutions in China, we designed a five-gene panel including BRAF/NRAS/KRAS/HRAS/TERT genes and conducted a retrospective study to evaluate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34318534
DOI: 10.1002/jcla.23920
PMCID: PMC8418506

Genes

BRAF
HRAS
KRAS
NRAS
TERT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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